Summary
Work History
Education
Skills
References
Publications
Personal Information
Awards
Timeline
Generic
Ayman M. Sweed

Ayman M. Sweed

Dokki,Giza

Summary

Accomplished Associate Professor of Organic Chemistry with over a decade of experience in medicinal and materials chemistry at a leading national research institute. Proven expertise in the multi-step synthesis, functionalization, and characterization of heterocyclic compounds, with a special focus on porphyrins for photodynamic therapy (PDT) and other biomedical applications. Adept at securing research funding, leading scientific projects, and publishing in high-impact journals (h-index: 8). Seeking to leverage extensive skills in synthetic chemistry and drug design to contribute to a world-class academic research program.

Work History

Associate Professor

National Research Centre
Egypt

Researcher

National Research Centre
Egypt

Researcher Assistant

National Research Centre
Egypt

Assistant Researcher

National Research Centre
Egypt

Education

PhD - Synthetic Organic Chemistry

Trinity College Dublin
01.2018

MSc - Organic Chemistry

Mansoura University
01.2011

Pre-MSc Studies - Organic Chemistry

Menoufeia University
01.2007

BSc - Chemistry

Menoufeia University
01.2004

Skills

  • Multi-step synthesis
  • Porphyrin Chemistry
  • Heterocyclic Chemistry
  • Photodynamic Therapy (PDT) Agents
  • Click Chemistry
  • Conjugation Chemistry
  • Organometallics
  • Purification
  • NMR (1D/2D)
  • Mass Spectrometry (MS)
  • HPLC
  • FT-IR
  • UV-Vis Spectroscopy
  • Structure Elucidation
  • Molecular Dynamic Simulations
  • ChemDraw
  • SciFinder
  • Reaxys

References

  • Prof. Dr. Ibrahim El Sayed, Professor of Organic Chemistry, University of Menoufeia, Department of Chemistry, Faculty of Science, ibrahimtantawy@yahoo.co.uk
  • Prof. Dr. Mathias O. Senge, Professor, Trinity Biomedical Sciences Institute, Trinity College Dublin, mathias.senge@tcd.ie
  • Prof. Dr. David Aitken, Professor, Institut de Chimie Moléculaire et des Matériaux d'Orsay, Université Paris-Saclay, david.aitken@universite-paris-saclay.fr

Publications

  • Manie, E. A., Elzayat, E. M., Ragab, S. S., Sweed, A. M., Ibrahim, H., Nasser, S., Allayeh, A. K., A novel approach utilizing spirocyclic thiopyrimidinone compounds against herpes simplex virus with underlying antiviral mechanisms of action., Virology Journal, 22, 2025, 97
  • Sweed, A.M., Ragab, S.S., Fikry M., R.A. Mohamed-Ezzat, Shaker,Y.M., Click Approach for Synthesis of 1,4-Disubstituted-1,2,3-triazoles of Porphyrin-isatin/sulfadrugs Conjugates Based on m-THPP, Journal of Porphyrins and Phthalocyanines, 28, 2024, 503-514
  • Ragab, S.S., Sweed, A. M, Srour, A., Synthesis and Antiproliferative Properties of Some Spirocyclic Pyrimidine Hydrazones., Chemistry Select, 9, 2024, e202400161
  • Sweed, A. M., SS Ragab, YM Shaker, MTHPP monoacetic ester: unexpected formation, zinc metalation, thermal and photophysical properties, Journal of the Iranian Chemical Society, 26, 2023
  • Sherif S. Ragab, Mohamed Abdelroaf, Ahmed Elrashidy, Ayman M. Sweed, Design, synthesis, Molecular Dynamic Simulation Studies, and Antibacterial evaluation of new Spirocyclic aminopyrimidines, Journal of Molecular Structure, 1278, 2023, 134912
  • AMK Sweed, SS Ragab, YM Shaker, Synthesis and characterization of asymmetric oxyacetamide bridged porphyrin conjugates embedded with N-containing heterocycles, Journal of Porphyrins and Phthalocyanines, 26, 2022, 2114-2122
  • FAA El-Hag, AA Elrashedy, AMK Sweed, EF Ewies, MA Abd-El-Maksoud, Synthesis, biological activity, and in silico studies of thieno [2, 3-d] pyrimidine and thieno [2, 3-d] triazine derivatives, Egyptian Pharmaceutical Journal, 21, 3, 2022, 360
  • Ragab, S.S., Sweed, A.M.K., Hamza, Z.K., Shaban, E., El-Sayed, A.A., Design, Synthesis, Antiviral Evaluation, and Molecular Dynamics Simulation Studies of New Spirocyclic Thiopyrimidinones as Anti HCoV-229E, Chemistry and Biodiversity, 19, 2022, e202200632
  • Mohamed S. Hasanin, Mohamed Abdelraof, Mohamed Fikry, Yasser M.Shaker, Ayman M. K. Sweed, Mathias O. Senge, Development of Antimicrobial Laser-induced Photodynamic Therapy Based on Ethylcellulose/Chitosan Nanocomposite with 5,10,15,20-Tetrakis(m-hydroxyphenyl)porphyrin., Molecules, 26, 2021, 3551
  • Ayman M. K. Sweed, Mathias O. Senge, Sanaa M. Sh. Attaa, Dalia S. Farraga, Abdel-Rahman H. Abdel-Rahman, Yasser M. Shaker, Synthesis of amphiphilic meso-tetrasubstituted porphyrin-L-amino acid and -heterocyclic conjugates based on m-THPP., J. Porphyrins Phthalocyanines, 2018, 22, 997–1009
  • Moylan, C.; Sweed, A.M.K.; Shaker, Y.M.; Scanlan, E.M.; Senge, M.O., Lead structures for application in photodynamic therapy. 7. Efficient synthesis of amphiphilic glycosylated lipid porphyrin derivatives: refining the linker conjugation for potential PDT applications., Tetrahedron, 2015, 71, 4145-4153
  • Sanaa. M. Sh. Atta, Dalia. S. Farrag, Ayman. M. K. Sweed, A. H. Abdel-Rahman, Preparation of new polycyclic compounds derived from benzofurans and furochromones. An approach to novel 1,2,3-thia-, and selena-diazolofurochromones of anticipated antitumor activities., European J. Med. Chem., 2010, 45, 4920

Personal Information

Title: PhD

Awards

  • Best PhD Thesis Award, National Research Centre, Egypt, 05/01/18
  • PhD Postgraduate Award, Trinity College Dublin & Mansoura University, 06/27/13 - 07/01/15
  • Postdoctoral Fellowship, ICMMO, University of Paris-Saclay, 11/01/25 - 04/30/26

Timeline

Associate Professor

National Research Centre

Researcher

National Research Centre

Researcher Assistant

National Research Centre

Assistant Researcher

National Research Centre

PhD - Synthetic Organic Chemistry

Trinity College Dublin

MSc - Organic Chemistry

Mansoura University

Pre-MSc Studies - Organic Chemistry

Menoufeia University

BSc - Chemistry

Menoufeia University

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Ayman M. Sweed